Category: Review Article


  • Analyzing without Lysing

    Non-damaging Techniques for Monitoring Cells Studying the interior of cells offers insight to the biochemical processes occurring. However, the process of collecting data involves bursting the cell open in a process called lysing that may also destroy important biochemical interactions. Researchers at Stanford University and the University of Michigan are developing technologies at the micro-…

  • Expressing Missing Links

    Mapping RNA to DNA with MARGI Over the past decade, it has become much easier, quicker, and cheaper to sequence the human genome. Organizations, like 23&me, have even made it possible for anyone to understand about their genome and any downstream effects their genes have on their health. However, there is still a lot about…

  • Computing Levinthal’s Paradox: Protein Folding, Part 2

    In a previous post, we discussed how proteins fold into unique shapes that allow them to perform their biological functions. Through many physical and chemical properties, like hydrogen bonding and hydrophobicity, proteins are able to fold correctly. However, proteins can fold improperly, and sometimes these malformed peptides aggregate, leading to diseases like Alzheimer’s. How can…

  • As a Matter of Fact…

    This is the first article in the series Pocket Science. With it, I want to discuss the context and importance of recent research in shorter articles potentially with more visual media. I hope that this will help people be more interested with the research going on around the world and want to stay updated with…

  • How to Fold (and Misfold) a Protein

    Protein Folding Part 1 Originally posted by Michigan Science Writers Editors: David Mertz, Zulierys Santana-Rodriguez, and Scott Barolo Proteins do most of the work in your body: Depending on their shape, they can digest your food, fire your neurons, give color to your eyes and allow you to see colors. Proteins follow instructions encoded in…

  • The Private Side of Scientific Research

    Context in Privatizing Science The amount of funding going to science research with respect to the federal budget has been reduced greatly over the past few years. This may or not have lead to the increase in private organizations funding, but either way more projects and research institutions have been entirely sponsored by philanthropists and…

  • Going Against the Masters of Physics

    Understanding the Gravity of a New Theory Both the motions of planets orbiting around the sun and a pencil rolling off the table onto the floor are described by the gravity. However, despite this phenomena being so easily recognized, why and how it happens is still very much up to debate. Theories of gravity have…

  • Just a Wobble Away from Disease

      DNA, the genetic code of life, is read over a million times per day to make proteins, the biological molecules that do all the work in cells. If this process goes wrong then it leads to cell destruction or disease states such as cystic fibrosis or cancer. Luckily, the cell has a multitude repair…

  • Assessing Impact in Open Access and Conventional Journals

    Recently, a lab mate of mine presented a paper at our weekly research meeting. She ended her analysis saying that she was skeptical of the methods and the rigor of the results because it came from the open access journal PLOSOne. This got me thinking and realizing that even though scientists are constantly demanding data…

  • Peer Review in Open Access: Struggles and Successes in Obtaining Quality Articles

    The peer review process in science publication has been imperative in making sure that articles and journals written are based off data that was obtained ethically. With the push to make publications more transparent and cheaper, the importance and existence of peer reviewing have been called into question. How Peer Review Works Right Now It…